Conduct searches across multiple relevant databases (usually in health at least Medline, Embase and the Cochrane library are searched). Adapt searches to the characteristics of the database. Document any modifications when adapting your search to a new database e.g. Are the fields different? Does the database use different subject headings? Conduct supplementary searches across grey literature, as well as hand searching selected journals and by citation tracking to address bias from published results. Whenever possible consult with a librarian in regard to your search strategy, online tutorials and guidelines are available.
PRECISION vs SENSITIVITY
When searching for material for systematic reviews there is a tension between comprehensiveness (SENSITIVITY) and relevance (PRECISION). In general the more comprehensive the search the less relevant are the results.
SENSITIVITY = number of relevant reports identified/Total number of relevant reports in existence
PRECISION = number of relevant reports identified/Total number of reports identified (Cochrane Handbook for Systematic Reviews of Interventions).
Developing a search strategy is an iterative process. Search terms are modified, based on what has already been retrieved. There are diminishing returns for search efforts; after a certain stage, each additional unit of time invested in searching returns fewer references that are relevant to the review. The decision as to how much to invest in the search process may depend on several factors, such as the question a review addresses, and the resources that are available.
Databases used for the systematic review searching will vary according to the topic of the Systematic Review. Some of the major databases used for health research are listed below.
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Embase: European database of biomedical and pharmacologic literature. |
Cochrane Library: Includes information on the effects of interventions in health care. |
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Joanna Briggs Institute EBP (JBI): Provides evidence in various formats for nursing, allied health and medical professionals. |
Scopusislink opens in a newwindThislink opens in a new windo: Access to peer-reviewed titles in health, sciences, engineering, social sciences, psychology, and economics. |
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CINAHL Plus with Full Text: A collection of full text for nursing & allied health journals. |
Ovid Medline All: Includes the most complete version of Ovid MEDLINE.
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PsycINFO (a.k.a PsycNET): Resource for abstracts of scholarly journal articles, book chapters, books, and dissertations. |
See other discipline Subject Guides for more databases: Medicine, Psychology, Nursing and Midwifery,Social Work and Community, Health Science. |
A 2015 paper by Godin et al discusses a systematic process for searching grey literature that involves a combination of 4 different search strategies. These include "(1) grey literature databases, (2) customized Google search engines, (3) targeted websites, and (4) consultation with contact experts" (p.1). See the paper here for more details on the process and documentation.
Godin, K., Stapleton, J., Kirkpatrick, S. I., Hanning, R. M., & Leatherdale, S. T. (2015). Applying systematic review search methods to the grey literature: a case study examining guidelines for school-based breakfast programs in Canada. Systematic reviews, 4(1), 138. http://10.1186/s13643-015-0125-0

Systematic review literature searching requires detailed and documented searches across all relevant material. Publication bias can be mitigated by ensuring grey literature has also been thoroughly searched. Additionally hand searching of relevant journals and citation tracking are also usually included in a search protocol.
Grey Literature is information that is published by organizations whose primary task is not publication, e.g. government departments. Searching grey literature is one way to address potential bias in reporting of research results via published material. It can be a daunting task so search those resources that make the most sense for your research question.Here is a list of some grey literature sources and databases.
Australian Institute of Health and Welfare: Reliable, relevant information and statistics on Australia's health and welfare.
Open Grey: Open access to 700.000 bibliographical references of grey literature (paper) produced in Europe .
National Health and Medical Research Council: Health and medical research in Australia
State Health Departments: Access to reports, policy and information and more.
Australian Indigenous HealthInfoNet: Indigenous health research and other knowledge.
Trove: Australian University thesis.
Research Direct: Repository of Western Sydney University research.
Analysis and Policy Observatory: Australian policy research.
Clinical Trials: Database of clinical studies conducted around the world.
Australian Bureau of Statistics: National statistical agency of Australia.
Research Direct: Searchable repository of Western Sydney University research.
Check also relevant government departments and peak organizational webpages.
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